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    SKC800 AUTOMATIC STAINLESS STEEL BIOREACTOR

    SKC800 pilot and production stainless steel bioreactor provides a new solution for the development of bioprocess with its excellent performance and moderate scale.
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    SKC800 75L pilot and production stainless steel bioreactor provides new solutions for the development of bioprocesses

    with its excellent performance and moderate scale.

    It adopts the biological reaction process control algorithm independently developed by CEKG and has a highly

    controllable culture environment. Through stirring, temperature, pH, DO, deep ventilation, surface ventilation, peristaltic

    pump, defoaming and liquid level, weighing, The control of cold spot detection and additional analog input and output

    provide suitable cell growth conditions to achieve batch culture, fed-batch culture and continuous perfusion culture,

    thereby achieving high-density culture and high-yield production.

    For fabric carrier adherent culture, especially for secreted products, e.g. CHO for EPO/TPO,

    VERO cells for human rabies vaccine/Japanese encephalitis vaccine/COVID-19 vaccines/

    MDCK cells for flu vaccines, etc.

    For micro-carrier adherent culture, e.g. VERO cells/diploid cells for human rabies vaccine, etc

    For suspension cell culture, e.g. CHO cell antibody/SF9 cell cervical cancer vaccine, etc.

    Vessel volume

    Total volume

    40L                                   75L                                   150L                                  300L

    Working volume

    10.75-32.0L                         18.75-60.0L                         37.5-120.0L                         75.5-240.0L

    Control system

    Siemens PLC, Siemens touch screen, 3 pumps, Ethernet interface, USB interface

    Temperature control

    Agitating system

    Water jacket, electrical-heater PID automatic control, Pt100 sensor, control accuracy ±0.1℃, PID control, temperature control range 8-45℃ above, Max. 60℃

     

    Agitating form

    Upper mixing, double seal(Bottom magnetic stirring optional

    Impeller

    Pitched blade/basket impeller/cell lift impeller/spin filter impeller optional

    Agitating speed

    Load

    25-200rpm                          25-150rpm                          25-120rpm                          25-100rpm

     

    Weighing module

    0-40kg

    Cascaded by pump 

    0-100kg

    Cascaded by pump

    0-200kg

    Cascaded by pump

    0-300kg

    Cascaded by pump

    Sparger

    4 gas mixing, 1 or 4 thermal mass flow controllers optional

    Overlay ※

    4 gas mixing, 1 or 4 thermal mass flow controllers optional

    Exhaust

    Exhaust condenser, exhaust filter heater

    Gas distributor※

    Circinate. Micro and macro sparge optional

    pH※

    2-12, PID control cascaded by pumps/gas flow. ISM probe optional

    DO※

    0-200%, PID control, cascaded by agitation/pumps/gas flow. ISM probe/optical probe optional

    Sterilization

    Automatic SIP

    Cold spot detection 

    Optional, cold spot monitoring and FO value calculation during sterilization in place

    Pumps

    Fixed-speed pumps for addition/acid/base/anti-foam etc., speed 100PRM

    Level and anti-foam

    1 level probe. High level probe optional

    SCADA※

    Optional. GMP/GAMP standards.

    Utilities

    Water: 50um filtration; industrial steam 30-35PSIG, pure steam 30-35PSIG; 4 gases 30-35PSIG

     

     

    Power supply

    AC380V,50/60Hz

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    Wuhan CEKG TECH. Co., Ltd. owns its own brand CEKG, focusing on providing cell culture equipment and consumables for vaccine, cell and gene therapy, antibody, in vitro diagnosis and other industries. Through the unremitting efforts of the team, the company has become an advanced high-tech enterprise in the industry. It has applied for 46 patents, won the honorary title of high-tech enterprise, Wuhan City "Optical Valley Gazelle" enterprise and "Hubei Province Specialized, Special and new" enterprise, and passed the ISO9001 quality system certification.